DescriptionLearn all the microbiology and basic immunology concepts you need to know for your courses and exams. Now fully revised and updated, Mims’ clinically relevant, systems-based approach and abundant colour illustrations make this complex subject easy to understand and remember.Key FeaturesLearn about infections in the context of major body systems and understand why these are environments in which microbes can establish themselves, flourish, and give rise to pathologic changes. This systems-based approach to microbiology employs integrated and case-based teaching that places the ‘bug parade’ into a clinical context.Effectively review for problem-based courses with the help of chapter introductions and ‘Lessons in Microbiology’ text boxes that highlight the clinical relevance of the material, offer easy access to key concepts, and provide valuable review tools.Approach microbiology by body system or by pathogen through the accompanying electronic ‘Pathogen Parade’ – a quickly searchable, cross-referenced glossary of viruses, bacteria and fungiA new electronic ‘Vaccine Parade’ offers quick-reference coverage of the most commonly used vaccines in current clinical practiceDeepen your understanding of epidemiology and the important role it plays in providing evidence-based identification of key risk factors for disease and targets for preventative medicine.Grasp and retain vital concepts easily, with a user-friendly colour coded format, succinct text, key concept boxes, and dynamic illustrations.New and enhanced information reflects the growing importance of the human microbiota and latest molecular approachesAccess the complete contents on the go via the accompanying interactive eBook, with a range of bonus materials to enhance learning and retention – includes self-assessment materials and clinical cases to check your understanding and aid exam preparation.Table of ContentsSECTION 1 THE ADVERSARIES – PATHOGENSPathogens as parasitesThe bacteriaThe virusesThe fungiThe protozoaThe helminthsThe arthropodsPrionsThe host-parasite relationshipSECTION 2 THE ADVERSARIES – HOST DEFENCESThe innate defences of the bodyAdaptive immune responses bring specificityCooperation leads to effective immune responsesSECTION 3 THE CONFLICTSBackground to the infectious diseasesEntry, exit and transmissionImmune defences in actionSpread and replicationParasite survival strategies and persistent infectionsPathological consequences of infectionSECTION 4 CLINICAL MANIFESTATION AND DIAGNOSIS OF INFECTIONS BY BODY SYSTEMThe clinical manifestations of infectionUpper respiratory tract infectionsLower respiratory tract infectionsUrinary tract infectionsSexually transmitted infectionsGastrointestinal tract infectionsObstetric and perinatal infectionsCentral nervous system infectionsInfections of the eyeInfections of the skin, soft tissue, muscle and associated systemsVector-borne infectionsMultisystem zoonosesFever of unknown originInfections in the compromised hostSECTION 5 DIAGNOSIS AND CONTROLDiagnosis of infection and assessment of host defence mechanismsEpidemiology and control of infectious diseasesAttacking the enemy: antimicrobial agents and chemotherapyProtecting the host: vaccinationActive, passive and adoptive immunotherapyInfection controlAuthors BiographyRichard Goering, BA MSc PhD, Professor and Chair, Department of Medical Microbiology and Immunology, Creighton University School of Medicine, Omaha, Nebraska, USA;Hazel Dockrell, BA (Mod) PhD, Professor of Immunology, Department of Immunology and Infection, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK;Mark Zuckerman, BSc (Hons) MB BS MRCP MSc FRCPath, Consultant Virologist and Honorary Senior Lecturer, South London Specialist Virology Centre, King’s College Hospital NHS Foundation Trust, King’s College London School of Medicine, London, UK andPeter L. Chiodini, BSc, MBBS, PhD, MRCS, FRCP, FRCPath, FFTMRCPS(Glas), Honorary Professor, The London School of Hygiene and Tropical Medicine, Infectious & Tropical Diseases; Consultant Parasitologist, Hospital for Tropical Diseases, Department of Clinical Parasitology, London England UK