Bonetta Series · Cheek augmentation, jawline contouring, nose reshaping Bonetta Volume — High-Density HENM Filler for Facial Sculpting (2 × 1.1mL) Bonetta Volume is ExoCoBio’s highest-density variant — 24 mg/mL cross-linked HA 0.3% lidocaine with the most pronounced HENM cross-linking in the Bonetta range. Supplied as 2 × 1.1 mL syringes per box. Engineered for facial sculpting: cheek augmentation, jawline contouring, non-surgical nose reshaping, and chin augmentation with 12–24 month durability. Professional use only — for licensed aesthetic practitioners. Manufacturer: ExoCoBio Inc., South Korea · Established 2017 HENM Highest Density 2 × 1.1mL Per Box May 2026 Last Reviewed · Verified ExoCoBio Inc. Technology How Bonetta Volume Professional HA Filler Is Engineered 1 HENM Patented Cross-Linking (Highest Density) ExoCoBio Inc.’s proprietary cross-linking process produces a stabilised HA gel matrix engineered for sustained tissue retention. The technology balances viscoelasticity (firmness for projection) with extrusion smoothness (easier injection through the 27G needle). The result: predictable handling, consistent gel distribution, and 12–24 months durability in deep dermis placement. 2 Quality & Purity Non-animal hyaluronic acid produced by bacterial fermentation. Endotoxin levels controlled below international safety thresholds. Stringent manufacturing under GMP-certified conditions minimises BDDE residue, heavy metals, and protein contaminants — reducing the risk of post-injection inflammation, granuloma formation, or hypersensitivity reactions in suitable patient profiles. Composition Bonetta Volume Professional HA Filler Active Ingredients Cross-Linked Hyaluronic Acid 24 mg/mL Non-animal hyaluronic acid produced by bacterial fermentation, cross-linked using ExoCoBio Inc.’s HENM Patented Cross-Linking (Highest Density) technology. The cross-linking process creates a stable, durable gel matrix that resists rapid enzymatic breakdown in tissue. Phosphate-buffered saline carries the gel at near-physiological pH. Lidocaine HCl 0.3% (3 mg/mL) Premixed local anaesthetic at the industry-standard 0.3% concentration. Reduces injection-site discomfort and eliminates the need for on-site mixing with separate lidocaine vials. The lidocaine itself wears off within hours of injection and does not affect long-term gel duration. Clinical Indications Where Bonetta Volume Professional HA Filler Is Used Cheek Augmentation Primary indication. Deep subcutaneous and supraperiosteal placement for sustained midface volumising. 12–24 month durability per ExoCoBio data. Jawline & Chin Contouring Non-surgical jawline definition and chin augmentation. The high cross-linking density supports structural projection. Nose Reshaping Non-surgical rhinoplasty for nasal bridge and dorsum enhancement. Off-label use requiring advanced anatomical knowledge. Deep Wrinkle Correction Severe nasolabial folds and pronounced facial creases requiring high-firmness filler. Side-By-Side Bonetta Volume Professional HA Filler vs Juvederm vs Restylane Feature Bonetta Juvederm (Allergan) Restylane (Galderma) HA Concentration 24 mg/mL 15–24 mg/mL 20 mg/mL Cross-Linking Tech HENM Vycross / Hylacross NASHA® / OBT Lidocaine 0.3% (premixed) 0.3% (XC lines) 0.3% (Lidocaine variants) Duration 12–24 months 6–24 months (varies) 6–18 months (varies) Origin South Korea (ExoCoBio Inc.) USA (Allergan / AbbVie) Sweden (Galderma) Established Since 2017 2006 1996 ↔ Swipe horizontally on mobile to view all columns Comparison based on manufacturer published data. See our top dermal filler comparison guide for broader market context. Specifications Bonetta Volume Professional HA Filler Product Specifications Manufacturer Brand: Bonetta Company: ExoCoBio Inc. Country: South Korea Established: 2017 Formula HA Source: Non-animal bacterial fermentation HA Concentration: 24 mg/mL Lidocaine: 0.3% (3 mg/mL) premixed Cross-linking: HENM Patented Cross-Linking (Highest Density) Performance Duration: 12–24 months Injection Depth: Deep dermis · subcutaneous Recommended Needle: 27G Last Reviewed: May 2026 Approval & Storage Approvals: KFDA registered · GMP certified Packaging: 2 × 1.1 mL pre-filled syringes per box Storage: 2–25 °C, do not freeze Shelf life: 24 months unopened Verify regulatory status at the official Korean MFDS database — nedrug.mfds.go.kr. For market pricing context, see our dermal filler pricing guide. FAQs Bonetta Volume Professional HA Filler — Frequently Asked Questions What is Bonetta Volume Professional HA Filler? Bonetta Volume is ExoCoBio’s highest-density variant — 24 mg/mL cross-linked HA 0.3% lidocaine with the most pronounced HENM cross-linking in the Bonetta range. Supplied as 2 × 1.1 mL syringes per box. Engineered for facial sculpting: cheek augmentation, jawline contouring, non-surgical nose reshaping, and chin augmentation with 12–24 month durability. Where is Bonetta Volume Professional HA Filler manufactured? Bonetta Volume Professional HA Filler is manufactured by ExoCoBio Inc., a South Korea-based medical device and pharmaceutical company established in 2017. The product is part of the Bonetta dermal filler range, which is distributed across multiple international markets. Regulatory status: KFDA registered · GMP certified. What is the HA concentration in Bonetta Volume Professional HA Filler? Bonetta Volume Professional HA Filler contains 24 mg/mL of cross-linked hyaluronic acid plus 0.3% (3 mg/mL) premixed lidocaine for injection comfort. The hyaluronic acid is non-animal, produced by bacterial fermentation and cross-linked using ExoCoBio Inc.’s HENM Patented Cross-Linking (Highest Density) technology. Phosphate-buffered saline at near-physiological pH carries the gel. How long do Bonetta Volume Professional HA Filler results last? Per ExoCoBio Inc.’s clinical data, Bonetta Volume Professional HA Filler delivers 12–24 months of correction depending on placement and patient factors. Duration depends on injection depth, dose, anatomical site, patient metabolism, and facial movement intensity. Deep dermis placement typically delivers the longer end of the duration range. What is the recommended injection depth for Bonetta Volume Professional HA Filler? Bonetta Volume Professional HA Filler is engineered for deep dermis · subcutaneous placement. The standard recommended needle is 27G, supplied in the syringe blister pack. Some practitioners prefer a blunt-tip cannula of equivalent gauge for safer placement in highly vascular zones, particularly for deeper subcutaneous work. Is Bonetta Volume Professional HA Filler FDA approved or CE marked? Bonetta Volume Professional HA Filler regulatory status: KFDA registered · GMP certified. The product’s KFDA registration in South Korea is the primary regulatory baseline. CE marking and other international approvals enable distribution in the EU and other regulated markets. US FDA status varies — buyers in regulated jurisdictions should verify approval scope before importation and clinical use. How should Bonetta Volume Professional HA Filler be stored at the clinic? Store Bonetta Volume Professional HA Filler between 2 °C and 25 °C in original packaging, away from direct sunlight. Do not freeze — freezing damages the HA gel structure. Shelf life is typically 24 months from the manufacturing date printed on the box when unopened. Once a syringe is opened, contents must be used immediately. Partial syringes cannot be retained for later use due to sterility risk. Does Bonetta Volume Professional HA Filler contain animal-derived ingredients? No. Bonetta Volume Professional HA Filler uses non-animal hyaluronic acid produced by bacterial fermentation — the standard manufacturing approach for modern HA dermal fillers. The product contains no animal proteins or by-products, making it suitable for patients who avoid animal-derived medical products. The product is contraindicated in patients with severe allergies to gram-positive bacterial proteins (used in HA fermentation). Can Bonetta Volume Professional HA Filler be combined with other dermal fillers in the same session? Yes — layered protocols combining different fillers are standard aesthetic practice. Bonetta Volume Professional HA Filler can be combined with other Korean or international HA fillers, neuromodulators (botulinum toxin), or biostimulators (PLLA, calcium hydroxylapatite) within a single session. Always wait the recommended interval between different injectable products and confirm biocompatibility per each manufacturer’s IFU. How long do Bonetta Volume results last? Per ExoCoBio clinical data, Bonetta Volume delivers 12–24 months of correction in deep subcutaneous placements. The 24-month upper range applies to cheek augmentation and other low-movement zones with lower metabolic turnover. Dynamic areas like the jawline and chin typically deliver the 12–18 month range. Individual duration depends on dose, anatomical site, patient metabolism, and facial movement intensity. 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Browse category → Important Safety Information Read Before Clinical Use Bonetta Volume Professional HA Filler is a prescription medical device for use only by licensed aesthetic practitioners. Common reactions include injection-site bruising, swelling, redness, and tenderness — generally resolving within days. Deep placement (subcutaneous and supraperiosteal layers) involves heightened anatomical awareness of facial vasculature; practitioners require access to hyaluronidase for emergency dissolution. Like all hyaluronic acid dermal fillers, treatment carries rare but serious vascular complication risks. Contraindicated in patients with known hypersensitivity to hyaluronic acid or lidocaine, active skin infection at the treatment site, pregnancy, or breastfeeding. Full contraindications, vascular complication protocols, aftercare, and emergency guidance are detailed on the dermal filler safety page. Read Full Dermal Filler Safety Information → Bonetta is a registered trademark of ExoCoBio Inc.. Fillersfairy.com is a channel distributor and does not provide medical advice. This page is for informational purposes only and does not replace the manufacturer’s official Instructions for Use, which remains the authoritative source for clinical administration. Regulatory status varies by jurisdiction — buyers are responsible for verifying legal status before ordering. Last reviewed May 2026 against ExoCoBio Inc. manufacturer documentation.